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Article

Phenotypic and molecular analysis of six human cell lines derived from patients with plasma cell dyscrasia.

British journal of haematology - 1 Sept 1999

Gooding R P, Bybee A, Cooke F, Little A, Marsh S G, Coelho E, Gupta D, Samson D, Apperley J F

Abstract excerpt

Cell lines RPMI 8226, JJN3, U266 B1, NCI-H929 (all EBV-) and ARH77 and HS-Sultan (both EBV+) have been extensively characterized in this study. EBV- lines expressed the phenotype (CD138-, CD19+, CD20+) whereas EBV+ were (CD138+, CD19-, CD20-). CD56 expression was restricted to EBV- cell lines, with the exception of U266 B1, whereas PCA-1 was strongly expressed on five of the six cell lines. Only EBV+ cell lines...

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Identifiers

PMID: 10468855
DOI: 10.1046/j.1365-2141.1999.01602.x

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