Article
Breast cancer susceptibility genes. BRCA1 and BRCA2.
Medicine - 1 May 1998
Brody L C, Biesecker B B
Abstract excerpt
Mutations in the BRCA1 and BRCA2 genes lead to an increased susceptibility to breast, ovarian, and other cancers. It is estimated that 3%-8% of all women with breast cancer will be found to carry a mutation in 1 of these genes. Families with multiple affected first-degree relatives and patients with early-onset disease have been found to harbor mutations at a higher frequency. The BRCA1 and BRCA2 genes code for...
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