Breast cancer susceptibility genes. BRCA1 and BRCA2.

doi:10.1097/00005792-199805000-00006

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Article

Breast cancer susceptibility genes. BRCA1 and BRCA2.

Medicine - 1 May 1998

Brody L C, Biesecker B B

Abstract excerpt

Mutations in the BRCA1 and BRCA2 genes lead to an increased susceptibility to breast, ovarian, and other cancers. It is estimated that 3%-8% of all women with breast cancer will be found to carry a mutation in 1 of these genes. Families with multiple affected first-degree relatives and patients w...

Topics

Aged
Aged, 80 and over
Alleles
BRCA2 Protein
Breast Neoplasms
Chromosomes, Human, Pair 13
Chromosomes, Human, Pair 17
Exons
Female
Genes, BRCA1
Genetic Linkage
Genetic Testing
Humans
Middle Aged
Neoplasm Proteins
Pedigree
Point Mutation
Risk Factors

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