Article
Inherited breast cancer.
The Surgical clinics of North America - 1 Apr 1996
Radford D M, Zehnbauer B A
Abstract excerpt
Five to ten percent of breast cancer is attributable to the autosomal dominant inheritance of a high-risk susceptibility gene. There are a number of known inherited cancer syndromes that confer a higher risk of breast cancer. Recently, the BRCA1 gene, which is responsible for 45% of hereditary ea...
Topics
- Ataxia Telangiectasia
- BRCA1 Protein
- BRCA2 Protein
- Breast Neoplasms
- DNA Mutational Analysis
- DNA, Neoplasm
- Female
- Genetic Markers
- Hamartoma Syndrome, Multiple
- Humans
- Li-Fraumeni Syndrome
- Mutation
- Neoplasm Proteins
- Risk Assessment
- Transcription Factors