Article
Inherited breast cancer.
The Surgical clinics of North America - 1 Apr 1996
Radford D M, Zehnbauer B A
Abstract excerpt
Five to ten percent of breast cancer is attributable to the autosomal dominant inheritance of a high-risk susceptibility gene. There are a number of known inherited cancer syndromes that confer a higher risk of breast cancer. Recently, the BRCA1 gene, which is responsible for 45% of hereditary early-onset breast cancer and for the majority of co-inheritance of breast and ovarian cancer, has been cloned. Another...
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