Article
Is the hemochromatosis gene a modifier locus for cystic fibrosis?
Genetic testing - 1 Jan 1998
Rohlfs E M, Shaheen N J, Silverman L M
Abstract excerpt
The variable clinical manifestations of cystic fibrosis (CF) suggest the influence of modifier genes. For example, meconium ileus is present in approximately 10-15% of neonates with cystic fibrosis; however, the genetic and, or environmental factors that determine whether an individual will develop this complication have not been determined. We propose the HFE gene as a candidate modifier locus for CF based on...
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