Article
Cystic fibrosis modifier genes.
Journal of the Royal Society of Medicine - 1 Jan 2005
Davies Jane, Alton Eric, Griesenbach Uta
Abstract excerpt
Since the recognition that CFTR genotype was not a good predictor of pulmonary disease severity in CF, several candidate modifier genes have been identified. It is unlikely that a single modifier gene will be found, but more probable that several haplotypes in combination may contribute, which in itself presents a major methodological challenge. The aims of such studies are to increase our understanding of...
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