Article
[Aldose reductase gene polymorphism and rate of appearance of retinopathy in non insulin dependent diabetics].
Revista medica de Chile - 1 Apr 1999
Olmos P, Acosta A M, Schiaffino R, Díaz R, Alvarado D, O'Brien A, Muñoz X, Arriagada P, Claro J C, Vega R, Vollrath V, Velasco S, Emmerich M, Maiz A
Abstract excerpt
BACKGROUND: Recent studies suggest that polymorphisms associated to the aldose reductase gene could be related to early retinopathy in noninsulin dependent diabetics (NIDDM). There is also new interest on the genetic modulation of coagulation factors in relation to this complication. AIM: To look for a possible relationship between the rate of appearance of retinopathy and the genotype of (AC)n polymorphic marker...
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