[Polymorphism of the chymase gene and development of retinopathy in type 2 diabetic patients].

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Article

[Polymorphism of the chymase gene and development of retinopathy in type 2 diabetic patients].

Polskie Archiwum Medycyny Wewnetrznej - 1 Jul 2000

Sliwa-Strojek K, Grzeszczak W, Romaniuk W, Dorecka M, Kozera A

Abstract excerpt

Diabetic retinopathy is one of the major causes of blindness in developed countries. Among the factors involved in development of retinopathy genetic factors related to the generation of angiotensin II are mentioned. Recently was described that tissue chymase enzyme is the alternative trait for angiotensin II formulation. The aim of the study was assessment of association of CMA/B hCC polymorphism of chymase gene...

Topics

Chymases
Diabetes Mellitus, Type 2
Diabetic Retinopathy
Disease Progression
Female
Genotype
Humans
Male
Middle Aged
Polymerase Chain Reaction
Polymorphism, Genetic
Serine Endopeptidases

Source

Open in PubMed

Identifiers

PMID: 11303326

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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