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Article

Cell-surface-bound Yersinia translocate the protein tyrosine phosphatase YopH by a polarized mechanism into the target cell.

Molecular microbiology - 1 Oct 1995

Persson C, Nordfelth R, Holmström A, Håkansson S, Rosqvist R, Wolf-Watz H

Abstract excerpt

YopH is translocated by cell-surface-bound bacteria through the plasma membrane to the cytosol of the HeLa cell. The transfer mechanism is contact dependent and polarizes the translocation to only occur at the contact zone between the bacterium and the target cell. More than 99% of the PTPase act...

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Identifiers

PMID: 8596454
DOI: 10.1111/j.1365-2958.1995.mmi_18010135.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-8596454-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Cell-surface-bound Yersinia translocate the protein tyrosine phosphatase YopH by a polarized mechanism into the target cell.PMID 8596454Read ↗

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Status of YopM and YopN in the Yersinia Yop virulon: YopM of Y.enterocolitica is internalized inside the cytosol of PU5-1.8 macrophages by the YopB, D, N delivery apparatus.Semantic proximity Read ↗

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Yersinia enterocolitica TyeA, an intracellular regulator of the type III machinery, is required for specific targeting of YopE, YopH, YopM, and YopN into the cytosol of eukaryotic cells.Semantic proximity Read ↗

Regulation of Yersinia Yop-effector delivery by translocated YopE.Semantic proximity Read ↗

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Contribution of YopB to virulence of Yersinia enterocolitica.Semantic proximity Read ↗

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