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Article

Naringenin and interindividual variability in interaction of coumarin with grapefruit juice.

Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie - 1 Jul 1999

Bourian M, Runkel M, Krisp A, Tegtmeier M, Freudenstein J, Legrum W

Abstract excerpt

UNLABELLED: Grapefruit juice has been shown to enhance oral bioavailability of several drugs including coumarin. The degree of the interaction is highly variable among the individuals. OBJECTIVE: The aim of the study was to evaluate the interindividual variability in the pharmacokinetic profile o...

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PMID: 10445384
DOI: 10.1016/S0940-2993(99)80008-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-10445384-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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