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Article

Polymorphic X-chromosome inactivation of the human TIMP1 gene.

American journal of human genetics - 1 Sept 1999

Anderson C L, Brown C J

Abstract excerpt

X inactivation silences most but not all of the genes on one of the two X chromosomes in mammalian females. The human X chromosome preserves its activation status when isolated in rodent/human somatic-cell hybrids, and hybrids retaining either the active or inactive X chromosome have been used to assess the inactivation status of many X-linked genes. Surprisingly, the X-linked gene for human tissue inhibitor of...

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Source

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Identifiers

PMID: 10441576
DOI: 10.1086/302556
PMCID: PMC1377976

Genes

TIMP1
ELK1
ZNF41

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Polymorphic X-chromosome inactivation of the human TIMP1 gene.PMID 10441576Read ↗

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Heterogeneous gene expression from the inactive X chromosome: an X-linked gene that escapes X inactivation in some human cell lines but is inactivated in others.Semantic proximity Read ↗

Analysis of expressed SNPs identifies variable extents of expression from the human inactive X chromosome.Semantic proximity Read ↗

X-inactivation profile reveals extensive variability in X-linked gene expression in females.Semantic proximity Read ↗

Allele-specific underacetylation of histone H4 downstream from promoters is associated with X-inactivation in human cells.Semantic proximity Read ↗

Determination of X-chromosome inactivation status using X-linked expressed polymorphisms identified by database searching.Semantic proximity Read ↗

Abnormal X chromosome inactivation and tumor development.Semantic proximity Read ↗

Inactive X chromosome-specific reduction in placental DNA methylationSemantic proximity Read ↗

Genes that escape from X inactivation.Semantic proximity Read ↗

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