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Article

Retinoic acid promotes rod photoreceptor differentiation in rat retina in vivo

1 Aug 1999

Abstract excerpt

Previous studies have indicated that retinoic acid (RA) promotes rod photoreceptor differentiation in dissociated cultures of rat retina and in zebrafish embryos. To determine whether RA will have the same affect in the mammalian retina in vivo, pregnant rats were given single i.p. injections of RA on the 18th and 20th days of gestation, and the retinas of the pups were analyzed for rods. HPLC showed that i.p....

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PMID: 10439469
DOI: 10.1097/00001756-199908020-00031

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