Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Neuron-targeted gene transfer by adenovirus carrying neural-restrictive silencer element.

Neuroreport - 2 Aug 1999

Miyaguchi K, Maeda Y, Kojima T, Setoguchi Y, Mori N

Abstract excerpt

Adenovirus transfers genes to a wide range of cell types, but its application to neurons has been hampered by its reduced efficiency of infection as compared with that for glia. To achieve neuron-targeted gene transfer, we have produced an adenovirus carrying the reporter lacZ gene driven by the SCG10 minimum promoter containing the neural-restrictive silencer element (NRSE), which element selectively represses...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenoviridae
Share to Adenoviridae Infections
Share to beta-Galactosidase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Transfer Techniques

Share to In Vitro Techniques

Share to Neuroglia

Share to Pyramidal Cells

Share to Rats, Sprague-Dawley

Source

Identifiers

PMID: 10439462
DOI: 10.1097/00001756-199908020-00024

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Neuron-targeted gene transfer by adenovirus carrying neural-restrictive silencer element.PMID 10439462Read ↗

Gene Transfer into Neurons from Hippocampal Slices: Comparison of Recombinant Semliki Forest Virus, Adenovirus, Adeno-Associated Virus, Lentivirus, and Measles VirusSemantic proximity Read ↗

Adenoviral-Mediated, High-Level, Cell-Specific Transgene Expression: A SYN1-WPRE Cassette Mediates Increased Transgene Expression with No Loss of Neuron SpecificitySemantic proximity Read ↗

In vivo expression of beta-galactosidase in hippocampal neurons by HSV-mediated gene transfer.Semantic proximity Read ↗

The neuron-restrictive silencer element-neuron-restrictive silencer factor system regulates basal and endothelin 1-inducible atrial natriuretic peptide gene expression in ventricular myocytes.Semantic proximity Read ↗

Novel mutant Semliki Forest virus vectors: gene expression and localization studies in neuronal cells.Semantic proximity Read ↗

Silencer-mediated repression and non-mediated activation of BDNF and c-fos gene promoters in primary glial or neuronal cells.Semantic proximity Read ↗

Deletion of multiple immediate–early genes from herpes simplex virus reduces cytotoxicity and permits long-term gene expression in neuronsSemantic proximity Read ↗

Transcriptional regulation of the neuropeptide VGF by the neuron-restrictive silencer factor/neuron-restrictive silencer element.Semantic proximity Read ↗

Neuronal target genes of the neuron-restrictive silencer factor in neurospheres derived from fetuses with Down's syndrome: a gene expression studySemantic proximity Read ↗

A Borna disease virus vector for expression of foreign genes in neurons of rodents.Semantic proximity Read ↗

Engineered HSV vector achieves safe long-term transgene expression in the central nervous systemSemantic proximity Read ↗

Recombinant AAV-mediated gene delivery to the central nervous systemSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.