Article
[Angiotensin I-converting enzyme gene polymorphism and renal disease].
Rinsho byori. The Japanese journal of clinical pathology - 1 Nov 1997
Nakai K, Itoh C, Nakai K, Saito F, Ninomiya K, Sato M, Sudo M
Abstract excerpt
ACE inhibitor is known to have a therapeutic efficacy in renal diseases by reducing proteinuria and maintaining renal function. However, the relationship between ACE gene polymorphism and renal disease has not been fully elucidated. In this study, a 287 base pair(bp) I/D polymorphism of the ACE gene was examined with polymerase chain reaction(PCR) in 100 healthy subjects, 34 patients with chronic...
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