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Article

Lethal and teratogenic effects in two successive generations of the HLG mouse strain after radiation exposure of zygotes -- association with genomic instability?

Mutation research - 11 Aug 1999

Pils S, Müller W U, Streffer C

Abstract excerpt

We analysed the transmission of lethal and teratogenic events to the subsequent generation in HLG/Zte mice after exposure of the zygote stage to 1 Gy X-rays. As observed in previous studies, our results on teratogenic events occurring in the same generation, which was exposed during the zygote stage, reveal a significantly higher risk for the induction of gastroschisis. Interesting new insights came from the...

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Identifiers

PMID: 10434025
DOI: 10.1016/s0027-5107(99)00101-3

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Source receipt: pubmed, retrieved 7 Sept 2026.

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