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Article

Transgenerational transmission of radiation damage: genomic instability and congenital malformation.

Journal of radiation research - 1 Jan 2006

Streffer Christian

Abstract excerpt

The congenital malformation gastroschisis has a genetic disposition in the inbred mouse strain HLG/Zte. It is increased after preconceptional irradiation of males or females. Radiation exposures during the meiotic stages are most efficient. This malformation can also be induced by ionising radiation when the exposure takes place during the preimplantation period especially during the zygote stage. This latter...

Topics

Abnormalities, Radiation-Induced
Animals
Female
Gastroschisis
Genetic Predisposition to Disease
Genomic Instability
Male
Mice
Mice, Inbred C57BL
Mice, Inbred Strains
Preconception Injuries

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pregnancy

Radiation Injuries, Experimental

Sex Chromosome Aberrations

Zygote

Source

Identifiers

PMID: 17019048
DOI: 10.1269/jrr.47.b19

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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