Article
[Increased genomic instability in somatic cells of the progeny of female mice exposed to acute X-radiation in the preconceptional period].
Genetika - 1 Oct 2011
Lomaeva M G, Vasil'eva G V, Fomenko L A, Antipova V N, Gaziev A I, Bezlepkin V G
Abstract excerpt
The level of genome instability (GI) was studied in the progeny of female mice exposed in the preconceptional period to radiation doses of 0.5, 1, and 2 Gy in comparison to that in the progeny of the same parent pairs born before irradiation of the females. To assess the level of genome instability, we analyzed polymorphism of DNA fragments from postmitotic (blood and brain) and proliferating (spleen and tail...
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