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Article

Genetic polymorphism of merozoite surface protein-1 and merozoite surface protein-2 in Plasmodium falciparum field isolates from Myanmar.

Malaria journal - 17 May 2010

Kang Jung-Mi, Moon Sung-Ung, Kim Jung-Yeon, Cho Shin-Hyeong, Lin Khin, Sohn Woon-Mok, Kim Tong-Soo, Na Byoung-Kuk

Abstract excerpt

BACKGROUND: Merozoite surface protein-1 (MSP-1) and MSP-2 of Plasmodium falciparum are potential vaccine candidate antigens for malaria vaccine development. However, extensive genetic polymorphism of the antigens in field isolates of P. falciparum represents a major obstacle for the development of an effective vaccine. In this study, genetic polymorphism of MSP-1 and MSP-2 among P. falciparum field isolates from...

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Identifiers

PMID: 20478015
DOI: 10.1186/1475-2875-9-131
PMCID: PMC2878305

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