Article
Genetic polymorphism of merozoite surface protein-1 and merozoite surface protein-2 in Plasmodium falciparum field isolates from Myanmar.
Malaria journal - 17 May 2010
Kang Jung-Mi, Moon Sung-Ung, Kim Jung-Yeon, Cho Shin-Hyeong, Lin Khin, Sohn Woon-Mok, Kim Tong-Soo, Na Byoung-Kuk
Abstract excerpt
BACKGROUND: Merozoite surface protein-1 (MSP-1) and MSP-2 of Plasmodium falciparum are potential vaccine candidate antigens for malaria vaccine development. However, extensive genetic polymorphism of the antigens in field isolates of P. falciparum represents a major obstacle for the development o...
Topics
- Alleles
- Antigens, Protozoan
- Genotype
- Humans
- Malaria, Falciparum
- Merozoite Surface Protein 1
- Myanmar
- Plasmodium falciparum
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Protozoan Proteins
- Sequence Analysis, DNA