Article
Genetic variation in rates of nondisjunction: association of two naturally occurring polymorphisms in the chromokinesin nod with increased rates of nondisjunction in Drosophila melanogaster.
Genetics - 1 Aug 1999
Zwick M E, Salstrom J L, Langley C H
Abstract excerpt
Genetic variation in nondisjunction frequency among X chromosomes from two Drosophila melanogaster natural populations is examined in a sensitized assay. A high level of genetic variation is observed (a range of 0.006-0.241). Two naturally occurring variants at the nod locus, a chromokinesin required for proper achiasmate chromosome segregation, are significantly associated with an increased frequency of...
Topics
- Animals
- Chromosome Inversion
- Crosses, Genetic
- Drosophila Proteins
- Drosophila melanogaster
- Female
- Genetic Variation
- Kinesins
- Male
- Microtubule Proteins
- Nondisjunction, Genetic
- Polymorphism, Genetic
- Temperature
- X Chromosome