Article
The lethal(1)TW-6cs mutation of Drosophila melanogaster is a dominant antimorphic allele of nod and is associated with a single base change in the putative ATP-binding domain.
Genetics - 1 Oct 1991
Rasooly R S, New C M, Zhang P, Hawley R S, Baker B S
Abstract excerpt
The l(1)TW-6cs mutation is a cold-sensitive recessive lethal mutation in Drosophila melanogaster, that affects both meiotic and mitotic chromosome segregation. We report the isolation of three revertants of this mutation. All three revert both the meiotic and mitotic effects as well as the cold sensitivity, demonstrating that all three phenotypes are due to a single lesion. We further show that these revertants...
Topics
- Adenosine Triphosphate
- Alleles
- Amino Acid Sequence
- Animals
- Base Composition
- Binding Sites
- Crosses, Genetic
- Drosophila melanogaster
- Female
- Genes, Dominant
- Genes, Lethal