Article
Transmitochondrial differences and varying levels of heteroplasmy in nuclear transfer cloned cattle.
Molecular reproduction and development - 1 Sept 1999
Hiendleder S, Schmutz S M, Erhardt G, Green R D, Plante Y
Abstract excerpt
To assess the extent of cytoplasmic genetic variability in cloned cattle produced by nuclear transplantation procedures, we investigated 29 individuals of seven male cattle clones (sizes 2-6) from two different commercial sources. Restriction enzyme and direct sequence analysis of mitochondrial DNA (mtDNA) detected a total of 12 different haplotypes. Transmitochondrial individuals (i.e., animals which share...
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