Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic recombination: Helicases and topoisomerases link up.

Current biology : CB - 15 Jul 1999

Wu L, Karow J K, Hickson I D

Abstract excerpt

RecQ helicases and topoisomerase III are both required for genome stability, particularly to prevent 'promiscuous' genetic recombination. A recent study demonstrates that, together, these enzymes can catalyse the interlinking of plasmid DNA, and suggests a novel mechanism for the control of recombination.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenosine Triphosphatases
Share to DNA Helicases
Share to DNA Topoisomerases, Type I

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, Fungal

Share to Nucleic Acid Conformation

Share to Plasmids

Share to Recombination, Genetic

Share to RecQ Helicases

Source

Identifiers

PMID: 10421567
DOI: 10.1016/s0960-9822(99)80325-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic recombination: Helicases and topoisomerases link up.PMID 10421567Read ↗

The role of DNA topoisomerases in recombination and genome stability: A double-edged sword?Semantic proximity Read ↗

The BLM dissolvasome in DNA replication and repair.Semantic proximity Read ↗

Homologous recombination and the roles of double-strand breaks.Semantic proximity Read ↗

Mechanism of homologous recombination: mediators and helicases take on regulatory functionsSemantic proximity Read ↗

RecQ helicases and topoisomerases: implications for genome stability in humans.Semantic proximity Read ↗

Human RECQ1 promotes restart of replication forks reversed by DNA topoisomerase I inhibitionSemantic proximity Read ↗

Conserved Themes but Novel Activities in Recombinases and TopoisomerasesSemantic proximity Read ↗

DNA topoisomerase-mediated illegitimate recombination.Semantic proximity Read ↗

Cohesin regulates homology search during recombinational DNA repair.Semantic proximity Read ↗

Illegitimate recombination induced by overproduction of DnaB helicase in Escherichia coli.Semantic proximity Read ↗

Functional fine-tuning between bacterial DNA recombination initiation and quality control systems.Semantic proximity Read ↗

Hin-mediated DNA knotting and recombining promote replicon dysfunction and mutation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.