Evidence for a genetic association between alleles of monoamine oxidase A gene and bipolar affective disorder.

doi:10.1002/ajmg.1320600413

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Article

Evidence for a genetic association between alleles of monoamine oxidase A gene and bipolar affective disorder.

American journal of medical genetics - 14 Aug 1995

Lim L C, Powell J, Sham P, Castle D, Hunt N, Murray R, Gill M

Abstract excerpt

We present evidence of a genetic association between bipolar disorder and alleles at 3 monoamine oxidase A (MAOA) markers, but not with alleles of a monoamine oxidase B (MAOB) polymorphism. The 3 MAOA markers, including one associated with low MAOA activity, show strong allelic association with e...

Topics

Alleles
Bipolar Disorder
Chromosome Mapping
Female
Genotype
Humans
Male
Minisatellite Repeats
Monoamine Oxidase
Psychiatric Status Rating Scales

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