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Article

Evidence for a genetic association between alleles of monoamine oxidase A gene and bipolar affective disorder.

American journal of medical genetics - 14 Aug 1995

Lim L C, Powell J, Sham P, Castle D, Hunt N, Murray R, Gill M

Abstract excerpt

We present evidence of a genetic association between bipolar disorder and alleles at 3 monoamine oxidase A (MAOA) markers, but not with alleles of a monoamine oxidase B (MAOB) polymorphism. The 3 MAOA markers, including one associated with low MAOA activity, show strong allelic association with each other but surprisingly not with MAOB. Our results are significant only for females, though the number of males in...

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Source

Identifiers

PMID: 7485270
DOI: 10.1002/ajmg.1320600413

Genes

MAOA
MAOB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evidence for a genetic association between alleles of monoamine oxidase A gene and bipolar affective disorder.PMID 7485270Read ↗

No evidence for allelic association between bipolar disorder and monoamine oxidase A gene polymorphisms.Semantic proximity Read ↗

Genetic association between monoamine oxidase and manic-depressive illness: comparison of relative risk and haplotype relative risk data.Semantic proximity Read ↗

Genetic association between monoamine oxidase A microsatellite and RFLP alleles and bipolar affective disorder: analysis and meta-analysis.Semantic proximity Read ↗

Analysis of the monoamine oxidase A (MAOA) gene in bipolar affective disorder by association studies, meta-analyses, and sequencing of the promoterSemantic proximity Read ↗

Association between bipolar disorder and monoamine oxidase A gene polymorphisms: results of a multicenter study.Semantic proximity Read ↗

Neither single-marker nor haplotype analyses support an association between monoamine oxidase A gene and bipolar disorder.Semantic proximity Read ↗

Association analysis between mood disorder and monoamine oxidase gene.Semantic proximity Read ↗

MAOA Variants and Genetic Susceptibility to Major Psychiatric Disorders.Semantic proximity Read ↗

Genetic associations with clinical characteristics in bipolar affective disorder and recurrent unipolar depressive disorderSemantic proximity Read ↗

Negative emotionality: monoamine oxidase B gene variants modulate personality traits in healthy humans.Semantic proximity Read ↗

Cluster B personality disorders are associated with allelic variation of monoamine oxidase A activity.Semantic proximity Read ↗

Association analysis between a functional polymorphism in the monoamine oxidase A gene promoter and severe mood disorders.Semantic proximity Read ↗

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