Article
Variations in the gene for vacuolating toxin, vacA, in Japanese isolates of Helicobacter pylori.
Microbios - 1 Jan 1999
Ueda T, Kawaguchi M, Saito T, Ishigaki M, Hamashima H, Sasatsu M, Arai T
Abstract excerpt
Each of 284 strains of Helicobacter pylori which had been isolated in Japan was shown, by use of the polymerase chain reaction (PCR), to be positive for the vacA genes. The amplified vacA genes generated by PCR were classified into six classes (five for the clinical isolates, and one which corresponded to the standard strains). Endoscopic analysis revealed that cases of gastritis were most likely to be associated...
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