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Article

Efficient killing of inhaled bacteria in DeltaF508 mice: role of airway surface liquid composition.

The American journal of physiology - 1 Jul 1999

McCray P B, Zabner J, Jia H P, Welsh M J, Thorne P S

Abstract excerpt

Cystic fibrosis mice have been generated by gene targeting but show little lung disease without repeated exposure to bacteria. We asked if murine mucosal defenses and airway surface liquid (ASL) Cl(-) were altered by the DeltaF508 cystic fibrosis transmembrane conductance regulator mutation. Naiv...

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Source

Identifiers

PMID: 10409246
DOI: 10.1152/ajplung.1999.277.1.L183

Genes

ASL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-10409246-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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