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Article

Telomerase activity in melanoma and non-melanoma skin cancer

11 Dec 1998

Abstract excerpt

Telomeres are specialized structures consisting of repeat arrays of TTAGGGn located at the ends of chromosomes. They are essential for chromosome stability and, in the majority of normal somatic cells, telomeres shorten with each cell division. Most immortalized cell lines and tumours reactivate telomerase to stabilize the shortening chromosomes. Telomerase activation is regarded as a central step in...

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Identifiers

PMID: 10408692
DOI: 10.1038/sj.bjc.6690010

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Telomerase activity in melanoma and non-melanoma skin cancerPMID 10408692Read ↗

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Telomerase Reverse Transcriptase Protein Expression Is More Frequent in Acral Lentiginous Melanoma Than in Other Types of Cutaneous MelanomaSemantic proximity Read ↗

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Telomerase Expression by Aberrant Methylation of the TERT Promoter in Melanoma Arising in Giant Congenital NeviSemantic proximity Read ↗

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