Article
[Association between variants of lipoprotein lipase and coronary heart disease in a Tunisian population].
Pathologie-biologie - 1 Jun 2012
Jelassi A, Jguirim I, Slimani A, Najah M, Hamda K B, Addad F, Hassine M, Maatouk F, Varret M, Slimane M N
Abstract excerpt
OBJECTIVE: Coronary artery disease (CAD) is a complex multifactorial disease due to the interaction of multiple genes variations and environmental factors. Genetic variants of lipoprotein lipase (LPL), a key enzyme in the hydrolysis of triglyceride rich particles, may contribute to CAD. We analysed here the frequency of LPL variants (p.Asp9Asn, p.Asn291Ser and p.Ser447X) in a Tunisian population as well as their...
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