Article
Pharbin, a novel inositol polyphosphate 5-phosphatase, induces dendritic appearances in fibroblasts.
Biochemical and biophysical research communications - 22 Jul 1999
Asano T, Mochizuki Y, Matsumoto K, Takenawa T, Endo T
Abstract excerpt
We have cloned a cDNA encoding a novel protein pharbin with a homology to inositol polyphosphate 5-phosphatases. Pharbin contains relatively well-conserved catalytic motifs for 5-phosphatase, a proline-rich sequence corresponding to the SH3-binding motif, and a sequence consistent with the CaaX motif at the C-terminus. COS-7 cells transfected with pharbin exhibited elevated hydrolytic activity on the 5-phosphate...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
