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Article

HLA-DR53 molecules are associated with susceptibility to celiac disease and selectively bind gliadin-derived peptides.

Immunogenetics - 1 Aug 1999

Clot F, Gianfrani C, Babron M C, Bouguerra F, Southwood S, Kagnoff M F, Troncone R, Percopo S, Eliaou J F, Clerget-Darpoux F, Sette A, Greco L

Abstract excerpt

Celiac disease (CD) patients usually express a DQ2 heterodimer, whose chains DQalpha1*0501/DQbeta1*0201, are encoded by the genes HLA-DQA1*0501 and DQB1*0201, respectively. Among the DQ2 carriers, the risk of developing disease was shown to correlate with the number of DQbeta1*0201 chains encoded. Studying two separate cohorts of Italian and Tunisian patients, we now show a significant association of celiac...

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Identifiers

PMID: 10398807
DOI: 10.1007/s002510050554

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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