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Article

Frequent 4-bp deletion in exon 9 of theSMAD4/MADH4 gene in familial juvenile polyposis patients

1 Aug 1999

Abstract excerpt

Familial juvenile polyposis (FJP) is a hamartomatous polyposis syndrome characterized by the appearance of juvenile polyps in the gastrointestinal tract. Patients with this syndrome are at an increased risk for cancer of the colon, stomach, and pancreas. Recently, germline mutations in the SMAD4/DPC4 gene (official symbol MADH4) have been found in the majority of patients suffering from FJP. We have examined 11...

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Identifiers

PMID: 10398437
DOI: 10.1002/(sici)1098-2264(199908)25:4<403::aid-gcc15>3.0.co;2-p

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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