Article
Single-nucleotide polymorphisms can cause different structural folds of mRNA.
Proceedings of the National Academy of Sciences of the United States of America - 6 Jul 1999
Shen L X, Basilion J P, Stanton V P
Abstract excerpt
Single-nucleotide polymorphisms (SNPs) are the most common type of genetic variation in man. Genes containing one or more SNPs can give rise to two or more allelic forms of mRNAs. These mRNA variants may possess different biological functions as a result of differences in primary or higher order structures that interact with other cellular components. Here we report the observation of marked differences in mRNA...
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