Article
Glutathione-linked enzymes in benign and malignant oesophageal tissue.
British journal of cancer - 1 Apr 1999
Levy R D, Oosthuizen M M, Degiannis E, Greyling D, Hatzitheofilou C
Abstract excerpt
Oxyradicals are involved in multiple mutational events and can contribute to the conversion of healthy cells to cancer cells. Glutathione (GSH) and the GSH-replenishing enzymes keep the antioxidant status of normal cells at a level where they can avert oxyradical derived mutations. The aim of this study was to determine whether in cancer cells the GSH-replenishing, GSH antioxidant and GSH-depleting enzymes were...
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