Article
[Behavioral and molecular effects of endogenic kynurenines deficit in the honeybee (Apis mellifera L.)].
Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova - 1 Jan 2000
Lopatina N G, Zachepilo T G, Chesnokova E G, Savvateeva-Popova E V
Abstract excerpt
The importance of tryptophan endogenous metabolites kynurenines in the long-term memory and functioning of the signal cascade GluR - LIMK1 - F-actin, mediating the long-term memory trace storage, was demonstrated. The deficit of kynurenines induced by allopurinol (tryptophanoxygenase inhibitor) suppressed the long-term memory, decreased the LIMK1 expression, and paradoxically increased the F-actin content in the...
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