Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interferon Regulatory Factor 8 Regulates RANTES Gene Transcription in Cooperation with Interferon Regulatory Factor-1, NF-κB, and PU.1

18 May 2006

Abstract excerpt

Interferon regulatory factor (IRF)-8 is a member of the IRF family of transcription factors important in interferon-gamma-mediated signaling and in the development and function of dendritic cells. Regulated on activation, normal T cell expressed and secreted (RANTES, or CCL5) is a member of the CC chemokine family of proteins, strongly chemoattractant for several important immune cell types in host defense...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytokine Signaling Pathways and Interactions
Share to Immune Cell Function and Interaction
Share to interferon and immune responses

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16707500
DOI: 10.1074/jbc.m602059200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interferon Regulatory Factor 8 Regulates RANTES Gene Transcription in Cooperation with Interferon Regulatory Factor-1, NF-κB, and PU.1PMID 16707500Read ↗

Role of IRF8 in immune cells functions, protection against infections, and susceptibility to inflammatory diseases.Semantic proximity Read ↗

A non-classical ISRE/ISGF3 pathway mediates induction of RANTES gene transcription by type I IFNs.Semantic proximity Read ↗

IRF8: Mechanism of Action and Health ImplicationsSemantic proximity Read ↗

Regulation of RANTES Chemokine Gene Expression Requires Cooperativity Between NF-κB and IFN-Regulatory Factor Transcription FactorsSemantic proximity Read ↗

The macrophage IRF8/IRF1 regulome is required for protection against infections and is associated with chronic inflammation.Semantic proximity Read ↗

Regulation of Interleukin-8 Gene ExpressionSemantic proximity Read ↗

Regulation of RANTES promoter activation in alveolar epithelial cells after cytokine stimulation.Semantic proximity Read ↗

The Transcription Factor IRF8 Activates Integrin-Mediated TGF-β Signaling and Promotes NeuroinflammationSemantic proximity Read ↗

IRF4 and its regulators: evolving insights into the pathogenesis of inflammatory arthritis?Semantic proximity Read ↗

The Role of Interferon Regulatory Factors in Liver DiseasesSemantic proximity Read ↗

MultiplecisRegulatory Elements Control RANTES Promoter Activity in Alveolar Epithelial Cells Infected with Respiratory Syncytial VirusSemantic proximity Read ↗

IRF5 controls both acute and chronic inflammationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.