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Article

FKHR binds the insulin response element in the insulin-like growth factor binding protein-1 promoter.

Endocrinology - 1 Jul 1999

Durham S K, Suwanichkul A, Scheimann A O, Yee D, Jackson J G, Barr F G, Powell D R

Abstract excerpt

The insulin response element (IRE) in the IGFBP-1 promoter, and in other gene promoters, contains a T(A/G)TTT motif essential for insulin inhibition of transcription. Studies presented here test whether FKHR may be the transcription factor that confers insulin inhibition through this IRE motif. I...

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PMID: 10385407
DOI: 10.1210/endo.140.7.6856

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-10385407-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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