Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Regulation of insulin-like growth factor binding protein-1 promoter activity by FKHR and HOXA10 in primate endometrial cells.

Biology of reproduction - 1 Jan 2003

Kim J Julie, Taylor Hugh S, Akbas G Eda, Foucher Isabelle, Trembleau Alain, Jaffe Randal C, Fazleabas Asgerally T, Unterman Terry G

Abstract excerpt

Insulin-like growth factor binding protein-1 (IGFBP-1) is abundantly expressed in the liver and decidualized endometrium. FKHR, a FOXO forkhead transcription factor, stimulates IGFBP-1 promoter activity in liver cells through the insulin response sequences (IRSs). HOXA10, a homeobox transcription factor, is important in the decidualization process. Here we show that FKHR and HOXA10 are expressed in baboon...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Endometrium
Share to Forkhead Box Protein O1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Forkhead Transcription Factors

Share to Homeodomain Proteins

Share to Insulin-Like Growth Factor Binding Protein 1

Share to Sequence Deletion

Share to Sequence Homology, Nucleic Acid

Source

Identifiers

PMID: 12493691
DOI: 10.1095/biolreprod.102.009316

Genes

HOXA10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Regulation of insulin-like growth factor binding protein-1 promoter activity by FKHR and HOXA10 in primate endometrial cells.PMID 12493691Read ↗

Enhancer- and silencer-like sequences that mediate insulin-like growth factor-binding protein-2 gene expression in uterine cells of pregnancy.Semantic proximity Read ↗

FKHR binds the insulin response element in the insulin-like growth factor binding protein-1 promoter.Semantic proximity Read ↗

Correlation between FOXO1a (FKHR) and FOXO3a (FKHRL1) binding and the inhibition of basal glucose-6-phosphatase catalytic subunit gene transcription by insulin.Semantic proximity Read ↗

Recent Insights into Insulin-Like Growth Factor Binding Protein 2 Transcriptional RegulationSemantic proximity Read ↗

Phosphorylation of Serine 256 by Protein Kinase B Disrupts Transactivation by FKHR and Mediates Effects of Insulin on Insulin-like Growth Factor-binding Protein-1 Promoter Activity through a Conserved Insulin Response SequenceSemantic proximity Read ↗

The distal upstream region of insulin-like growth factor–binding protein-1 enhances its expression in endometrial stromal cells during decidualizationSemantic proximity Read ↗

Intronic hormone response elements mediate regulation of FKBP5 by progestins and glucocorticoids.Semantic proximity Read ↗

Role of three FKHR phosphorylation sites in insulin inhibition of FKHR action in hepatocytes.Semantic proximity Read ↗

Functional association of PR and CCAAT/enhancer-binding protein beta isoforms: promoter-dependent cooperation between PR-B and liver-enriched inhibitory protein, or liver-enriched activatory protein and PR-A in human endometrial stromal cells.Semantic proximity Read ↗

Insulin-like growth factor system gene expression in human endometrium during the menstrual cycle.Semantic proximity Read ↗

Identification of upstream stimulatory factor binding sites in the human IGFBP3 promoter and potential implication of adjacent single-nucleotide polymorphisms and responsiveness to insulin.Semantic proximity Read ↗

Cyclic AMP-induced Forkhead Transcription Factor, FKHR, Cooperates with CCAAT/Enhancer-binding Protein β in Differentiating Human Endometrial Stromal CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.