Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

QT interval is linked to 2 long-QT syndrome loci in normal subjects.

Circulation - 22 Jun 1999

Busjahn A, Knoblauch H, Faulhaber H D, Boeckel T, Rosenthal M, Uhlmann R, Hoehe M, Schuster H, Luft F C

Abstract excerpt

BACKGROUND: The rate-corrected QT interval (QTc) is heritable, and the discovery of quantitative trait loci that influence the QTc would be an important step in identifying the genes responsible for life-threatening arrhythmias in the general population. We studied 66 pairs of unselected normal dizygotic (DZ) twin subjects and their parents in a sib-pair analysis. We tested for linkage of gene loci harboring...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Human, Pair 11
Share to Chromosomes, Human, Pair 4

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA, Satellite

Share to Electrocardiography

Share to Genetic Linkage

Share to Long QT Syndrome

Share to Twins, Dizygotic

Share to Twins, Monozygotic

Source

Identifiers

PMID: 10377080
DOI: 10.1161/01.cir.99.24.3161

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

QT interval is linked to 2 long-QT syndrome loci in normal subjects.PMID 10377080Read ↗

Corrected QT Interval-Polygenic Risk Score and Its Contribution to Type 1, Type 2, and Type 3 Long-QT Syndrome in Probands and Genotype-Positive Family Members.Semantic proximity Read ↗

Risk stratification in the long-QT syndrome.Semantic proximity Read ↗

Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathwaysSemantic proximity Read ↗

Monogenic and Polygenic Contributions to QTc Prolongation in the PopulationSemantic proximity Read ↗

Risk for life-threatening cardiac events in patients with genotype-confirmed long-QT syndrome and normal-range corrected QT intervals.Semantic proximity Read ↗

Age-gender influence on the rate-corrected QT interval and the QT-heart rate relation in families with genotypically characterized long QT syndrome.Semantic proximity Read ↗

QT interval is a heritable quantitative trait with evidence of linkage to chromosome 3 in a genome-wide linkage analysis: The Framingham Heart StudySemantic proximity Read ↗

Genome-wide association study-identified novel genetic loci for QT interval in Taiwan: implications for population-specific arrhythmia risk.Semantic proximity Read ↗

Common genetic variants, QT interval, and sudden cardiac death in a Finnish population-based study.Semantic proximity Read ↗

Relation of increased short-term variability of QT interval to congenital long-QT syndrome.Semantic proximity Read ↗

Single nucleotide polymorphism map of five long-QT genes.Semantic proximity Read ↗

The effect of sex and underlying disease on the genetic association of QT interval and sudden cardiac deathSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.