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Article

Use of the 16S--23S ribosomal genes spacer region in studies of prokaryotic diversity.

Journal of microbiological methods - 1 May 1999

García-Martínez J, Acinas S G, Antón A I, Rodríguez-Valera F

Abstract excerpt

The description of microbial diversity by molecular culture-independent techniques most often involves the amplification of the 16S rRNA by PCR gene and either analysis of the diversity of amplified molecules (community fingerprinting) that allows the simultaneous study of many samples or the cloning and sequencing of a significant amount of amplification products. The fact that between the 16S and the 23S genes...

Topics

Bacteria
Base Sequence
DNA, Bacterial
DNA, Ribosomal
Enterobacteriaceae
Genes, Bacterial
Genes, rRNA
Genetic Variation
Molecular Sequence Data
Prokaryotic Cells
RNA, Ribosomal, 16S

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

RNA, Ribosomal, 23S

Source

Identifiers

PMID: 10353800
DOI: 10.1016/s0167-7012(99)00011-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-10353800-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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