Article
Distribution of HLA class II alleles among Spanish patients with pemphigus vulgaris.
Tissue antigens - 1 Sept 1998
González-Escribano M F, Jiménez G, Walter K, Montes M, Perez-Bernal A M, Rodríguez M R, Conejo-Mir J S, Núñez-Roldán A
Abstract excerpt
Twenty-six unrelated Spanish Caucasian individuals affected by pemphigus vulgaris (PV) were HLA typed and frequencies compared with those of 200 ethnically matched healthy controls. Twenty-three out of 26 patients were HLA-DR4. The frequency of HLA-DR14 was also increased (31%; controls: 4%). Of the 23 patients positive for HLA-DR4, 21 carried the DRB1*0402 allele. Therefore, the frequency of HLA-DRB1*0402 among...
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