Article
HLA-DQA1, -DQB1 and -DRB1 genotyping in Japanese pemphigus vulgaris patients by the PCR-RFLP method.
Tissue antigens - 1 Oct 1994
Niizeki H, Inoko H, Mizuki N, Inamoto N, Watababe K, Hashimoto T, Nishikawa T
Abstract excerpt
We performed HLA-DQA1, -DQB1 and -DRB1 genotyping using the PCR-RFLP (polymerase chain reaction-restriction fragment length polymorphism) method for 32 Japanese pemphigus vulgaris (PV) patients. There was a significant association of either DQB1*0503 or DRB1*1405 with PV, and a negative associati...
Topics
- Alleles
- Disease Susceptibility
- Gene Frequency
- Genes, MHC Class II
- Genetic Predisposition to Disease
- Genotype
- HLA-DQ Antigens
- HLA-DQ alpha-Chains
- HLA-DQ beta-Chains
- HLA-DR Antigens
- HLA-DRB1 Chains
- Humans
- Japan
- Pemphigus
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length