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Article

Metabolic imbalance and sporulation in an isocitrate dehydrogenase mutant of Bacillus subtilis.

Journal of bacteriology - 1 Jun 1999

Matsuno K, Blais T, Serio A W, Conway T, Henkin T M, Sonenshein A L

Abstract excerpt

A Bacillus subtilis mutant with a deletion in the citC gene, encoding isocitrate dehydrogenase, the third enzyme of the tricarboxylic acid branch of the Krebs cycle, exhibited reduced growth yield in broth medium and had greatly reduced ability to sporulate compared to the wild type due to a block at stage I, i.e., a failure to form the polar division septum. In early stationary phase, mutant cells accumulated...

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Identifiers

PMID: 10348849
DOI: 10.1128/JB.181.11.3382-3391.1999
PMCID: PMC93804

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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