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Article

Role of acid metabolism in Streptomyces coelicolor morphological differentiation and antibiotic biosynthesis.

Journal of bacteriology - 1 May 2001

Viollier P H, Minas W, Dale G E, Folcher M, Thompson C J

Abstract excerpt

Studies of citrate synthase (CitA) were carried out to investigate its role in morphological development and biosynthesis of antibiotics in Streptomyces coelicolor. Purification of CitA, the major vegetative enzyme activity, allowed characterization of its kinetic properties. The apparent K(m) values of CitA for acetyl coenzyme A (acetyl-CoA) (32 microM) and oxaloacetate (17 microM) were similar to those of...

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Identifiers

PMID: 11325948
DOI: 10.1128/JB.183.10.3184-3192.2001
PMCID: PMC95220

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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