Article
A restriction fragment length polymorphism of a p53-related sequence in rat (Rattus norvegicus).
The Journal of veterinary medical science - 1 Feb 1994
Kunieda T, Ikadai H, Imamichi T, Toyoda Y
Abstract excerpt
Polymorphisms of the p53 tumor-suppressor gene and its related sequences were investigated among inbred rat strains. In a series of Southern blot hybridizations using the human p53 cDNA probe with various restriction endonucleases, HindIII digests and PstI digests showed interstrain variation in the length of hybridizing fragments. Distribution of the HindIII variant fragments among 17 inbred rat strains was...
Topics
- Alleles
- Animals
- Blotting, Southern
- Chromosome Mapping
- Genes, p53
- Genetic Markers
- Humans
- Polymorphism, Restriction Fragment Length
- Rats
- Rats, Inbred Strains
- Restriction Mapping
