A computer-assisted two-dimensional gel electrophoresis approach for studying the variations in protein expression related to an induced functional repression of NFkappaB in lymphoblastoid cell lines.

doi:10.1002/(SICI)1522-2683(19990101)20:4/5<1017::AID-ELPS1017>3.0.CO;2-K

Article

A computer-assisted two-dimensional gel electrophoresis approach for studying the variations in protein expression related to an induced functional repression of NFkappaB in lymphoblastoid cell lines.

Electrophoresis - 1 Jan 2000

Joubert-Caron R, Feuillard J, Kohanna S, Poirier F, Le Caër J P, Schuhmacher M, Bornkamm G W, Polack A, Caron M, Bladier D, Raphaël M

Abstract excerpt

Strategies are needed for conclusive interpretation of two-dimensional gel electrophoresis (2-D PAGE) maps in order to identify pertinent differences in protein expression during regulation of the transcription of discrete sets of genes. The model used in this study was a human lymphoblastoid cell line in which a functional repression of the transcription factors NFkappaB was obtained by induction of...

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A computer-assisted two-dimensional gel electrophoresis approach for studying the variations in protein expression related to an induced functional repression of NFkappaB in lymphoblastoid cell lines.

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