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Article

Quantifying Residual HIV-1 Replication in Patients Receiving Combination Antiretroviral Therapy

27 May 1999

Abstract excerpt

BACKGROUND: In patients infected with human immunodeficiency virus type 1 (HIV-1), combination antiretroviral therapy can result in sustained suppression of plasma levels of the virus. However, replication-competent virus can still be recovered from latently infected resting memory CD4 lymphocytes; this finding raises serious doubts about whether antiviral treatment can eradicate HIV-1. METHODS: We looked for...

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Identifiers

PMID: 10341272
DOI: 10.1056/nejm199905273402101

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