Discriminative stimulus (DS) properties of nicotine in the C57BL/6 mouse.

doi:10.1016/s0091-3057(98)00262-7

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Article

Discriminative stimulus (DS) properties of nicotine in the C57BL/6 mouse.

Pharmacology, biochemistry, and behavior - 1 May 1999

Varvel S A, James J R, Bowen S, Rosecrans J A, Karan L D

Abstract excerpt

Previous research conducted in this and other laboratories has examined the role of genetic factors in determining sensitivity to (-)-nicotine in a variety of behavioral and physiological measures in the rat. More recent research further indicates that genetic factors can also influence the level of sensitivity to (-)-nicotine when serving as a discriminative stimulus (DS) in different rat strains. However, there...

Topics

Analysis of Variance
Animals
Conditioning, Operant
Cues
Discrimination Learning
Dose-Response Relationship, Drug
Generalization, Stimulus
Genotype
Male
Mice
Mice, Inbred C57BL
Nicotine
Nicotinic Agonists
Stimulation, Chemical

Source

Open in PubMed

Identifiers

PMID: 10340520
DOI: 10.1016/s0091-3057(98)00262-7

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