Article
Association studies on beta2-adrenoceptor polymorphisms and enhanced IgE responsiveness in an atopic population.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Jun 1999
Deichmann K A, Schmidt A, Heinzmann A, Kruse S, Forster J, Kuehr J
Abstract excerpt
The beta2 adrenergic receptor 2 represents a cell surface receptor responsible for the binding of endogenous catecholamines and their exogenously administered agonists and antagonists, mediating their effects to the interior of the cell. On the basis of these functions, the observed association of two of its polymorphisms, Gly16 and Gln27, with nocturnal- and steroid-dependent asthma has been discussed. It has...
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