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Article

Bone morphogenetic proteins-2 and -4 attenuate apoptosis in a cerebellar primitive neuroectodermal tumor cell line

21 Apr 1999

Abstract excerpt

Similarities between primitive neuroectodermal tumors and central nervous system (CNS) progenitor cells have evoked interest in the response of these tumors to endogenous growth factors. The bone morphogenetic proteins (BMPs) have recently been found to regulate survival and differentiation of CNS progenitor cell populations. In this study, we investigated the effects of BMP-2, BMP-4, and BMP-6 on the...

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PMID: 10336254
DOI: 10.1002/(sici)1097-4547(19990501)56:3<248::aid-jnr4>3.0.co;2-u

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Source receipt: pubmed, retrieved 7 Sept 2026.

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