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Article

Isolation and characterization of the yeast las21 mutants, which are sensitive to a local anestheticum, tetracaine.

Genes & genetic systems - 1 Dec 1998

Tohe A, Oguchi T

Abstract excerpt

We isolated and characterized yeast mutants whose growth is sensitive to a local anestheticum tetracaine and, at the same time, temperature sensitive. These mutants were collectively called las mutants (local anestheticum sensitive). The las21 mutants were analyzed in this study. The wild type LAS21 gene was cloned by exploiting temperature sensitivity of the las21 mutants and we found that LAS21 encodes ORF...

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Identifiers

PMID: 10333567
DOI: 10.1266/ggs.73.365

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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