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Article

Both Transcriptional and Posttranscriptional Mechanisms Regulate Human Telomerase Template RNA Levels

1 Jun 1999

Abstract excerpt

The human telomerase RNA component (hTR) is present in normal somatic cells at lower levels than in cancer-derived cell lines. To understand the mechanisms regulating hTR levels in different cell types, we have compared the steady-state hTR levels in three groups of cells: (i) normal telomerase-negative human diploid cells; (ii) normal cells transfected with the human telomerase catalytic subunit, hTERT; and...

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Share to Advanced biosensing and bioanalysis techniques
Share to RNA Interference and Gene Delivery
Share to Telomeres, Telomerase, and Senescence

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Identifiers

PMID: 10330139
DOI: 10.1128/mcb.19.6.3989

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Both Transcriptional and Posttranscriptional Mechanisms Regulate Human Telomerase Template RNA LevelsPMID 10330139Read ↗

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