Article
Methods to estimate genetic components of variance for quantitative traits in family studies.
Genetic epidemiology - 1 Jan 1999
de Andrade M, Amos C I, Thiel T J
Abstract excerpt
The aim of this paper was to compare several methods of estimating the genetic components of a quantitative trait in familial data. The Expectation and Maximization (E-M) algorithm, the Newton-Raphson method, and the scoring method were compared for estimating polygenic and environmental effects on nuclear families. We also compared scoring and quasilikelihood (QL) methods when a linked genetic marker was...
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